La crisi pel COVID 19 ha permès a molts investigadors escriure i publicar articles científics i reviews. Aquesta és la llista d'articles que s'han publicat entre l'abril i principis de juny, amb autoria principal o amb la col·laboració d'investigadors de l'Institut Josep Carreras: Mechanisms of epigenetic inheritance of variable traits through the germline

Casas E, Vavouri T.

Reproduction. 2020 Jun;159(6):R251-R263.

doi: 10.1530/REP-19-0340

Treatment adapted to pregnancy in a patient with Burkitt lymphoma

Comes M, Batlle M, Ribera JM.

Med Clin (Barc). 2020 Jun 12;154(11):470-471.

doi: 10.1016/j.medcli.2019.04.038

Towards a more precise therapy in cancer: Exploring epigenetic complexity

Cossío FP, Esteller M, Berdasco M.

Curr Opin Chem Biol. 2020 May 29;57:41-49.

doi: 10.1016/j.cbpa.2020.04.008

Complement as the enabler of carfilzomib-induced thrombotic microangiopathy

Blasco M, Martínez-Roca A, Rodríguez-Lobato LG, Garcia-Herrera A, Rosiñol L, Castro P, Fernández S, Quintana LF, Cibeira MT, Bladé J, Fernández de Larrea C, Tovar N, Jimenez R, Poch E, Guillen E, Campistol JM, Carreras E, Diaz-Ricart M, Palomo M.

Br J Haematol. 2020 May 29.

doi: 10.1111/bjh.16796

An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.

Colli ML, Ramos-Rodríguez M, Nakayasu ES, Alvelos MI, Lopes M, Hill JLE, Turatsinze JV, Coomans de Brachène A, Russell MA, Raurell-Vila H, Castela A, Juan-Mateu J, Webb-Robertson BM, Krogvold L, Dahl-Jorgensen K, Marselli L, Marchetti P, Richardson SJ, Morgan NG, Metz TO, Pasquali L, Eizirik DL.

Nat Commun. 2020 May 22;11(1):2584.

doi: 10.1038/s41467-020-16327-0

Efficacy of extended infusion of β-lactam antibiotics for the treatment of febrile neutropenia in haematologic patients: protocol for a randomised, multicentre, open-label, superiority clinical trial (BEATLE)

Laporte-Amargos J, Gudiol C, Arnan M, Puerta-Alcalde P, Carmona-Torre F, Huguet M, Albasanz-Puig A, Parody R, Garcia-Vidal C, Del Pozo JL, Batlle M, Tebé C, Rigo-Bonnin R, Muñoz C, Padullés A, Tubau F, Videla S, Sureda A, Carratalà J.

Trials. 2020 May 18;21(1):412.

doi: 10.1186/s13063-020-04323-0

Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide

Im A, Rashidi A, Wang T, Hemmer M, MacMillan ML, Pidala J, Jagasia M, Pavletic S, Majhail NS, Weisdorf D, Abdel-Azim H, Agrawal V, Al-Homsi AS, Aljurf M, Askar M, Auletta JJ, Bashey A, Beitinjaneh A, Bhatt VR, Byrne M, Cahn JY, Cairo M, Castillo P, Cerny J, Chhabra S, Choe H, Ciurea S, Daly A, Perez MAD, Farhadfar N, Gadalla SM, Gale R, Ganguly S, Gergis U, Hanna R, Hematti P, Herzig R, Hildebrandt GC, Lad DP, Lee C, Lehmann L, Lekakis L, Kamble RT, Kharfan-Dabaja MA, Khandelwal P, Martino R, Murthy HS, Nishihori T, O'Brien TA, Olsson RF, Patel SS, Perales MA, Prestidge T, Qayed M, Romee R, Schoemans H, Seo S, Sharma A, Solh M, Strair R, Teshima T, Urbano-Ispizua A, Van der Poel M, Vij R, Wagner JL, William B, Wirk B, Yared JA, Spellman SR, Arora M, Hamilton BK.

Biol Blood Marrow Transplant. 2020 May 17:S1083-8791(20)30286-X.

doi: 10.1016/j.bbmt.2020.05.001.

Update of the recommendations for the determination of biomarkers in colorectal carcinoma:

National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology

García-Alfonso P, García-Carbonero R, García-Foncillas J, Pérez-Segura P, Salazar R, Vera R, Ramón Y Cajal S, Hernández-Losa J, Landolfi S, Musulén E, Cuatrecasas M, Navarro S.

Clin Transl Oncol. 2020 May 16.

doi: 10.1007/s12094-020-02357-z

The induction strategies administered in the treatment of multiple myeloma exhibit a deleterious effect on the endothelium

Martinez-Sanchez J, Palomo M, Torramade-Moix S, Moreno-Castaño AB, Rovira M, Gutiérrez-García G, Fernández-Avilés F, Escolar G, Penack O, Rosiñol L, Carreras E, Diaz-Ricart M. Bone Marrow Transplant. 2020 May 13.

doi: 10.1038/s41409-020-0947-9

Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

Eizirik DL, Pasquali L, Cnop M.

Nat Rev Endocrinol. 2020 May 12.

doi: 10.1038/s41574-020-0355-7

The DNA methylation landscape of human cancer organoids available at the American type culture collection

Joshi R, Castro De Moura M, Piñeyro D, Alvarez-Errico D, Arribas C, Esteller M.

Epigenetics. 2020 May 12:1-11.

doi: 10.1080/15592294.2020.1762398

Rare Anaemias, Sickle-Cell Disease and COVID-19

Vives Corrons JL, De Sanctis V.

Acta Biomed. 2020 May 11;91(2):216-217.

doi: 10.23750/abm.v91i2.9532

Sampling time-dependent artifacts in single-cell genomics studies

Massoni-Badosa R, Iacono G, Moutinho C, Kulis M, Palau N, Marchese D, Rodríguez-Ubreva J, Ballestar E, Rodriguez-Esteban G, Marsal S, Aymerich M, Colomer D, Campo E, Julià A, Martín-Subero JI, Heyn H.

Genome Biol. 2020 May 11;21(1):112.

doi: 10.1186/s13059-020-02032-0

RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment.

Torres-Gomez A, Sanchez-Trincado JL, Toribio V, Torres-Ruiz R, Rodríguez-Perales S, Yáñez-Mó M, Reche PA, Cabañas C, Lafuente EM.

Cells. 2020 May 8;9(5):E1166.

doi: 10.3390/cells9051166

Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT.

Sanz J, Galimard JE, Labopin M, Afanasyev B, Angelucci E, Ciceri F, Blaise D, Cornelissen JJ, Meijer E, Diez-Martin JL, Koc Y, Rovira M, Castagna L, Savani B, Ruggeri A, Nagler A, Mohty M; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT).

J Hematol Oncol.

2020 May 6;13(1):46.

doi: 10.1186/s13045-020-00882-6

The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner

Hurtado-Bagès S, Posavec Marjanovic M, Valero V, Malinverni R, Corujo D, Bouvet P, Lavigne AC, Bystricky K, Buschbeck M.

Cells. 2020 Apr 30;9(5):E1109.

doi: 10.3390/cells9051109

Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD(+) Dependent Lysine Deacetylases

Wössner N, Alhalabi Z, González J, Swyter S, Gan J, Schmidtkunz K, Zhang L, Vaquero A, Ovaa H, Einsle O, Sippl W, Jung M.

Front Oncol. 2020 Apr 30;10:657.

doi: 10.3389/fonc.2020.00657

The Exceptional Responders Initiative: Feasibility of A National Cancer Institute Pilot Study

Conley BA, Staudt L, Takebe N, Wheeler DA, Wang L, Cardenas MF, Korchina V, Zenklusen JC, McShane LM, Tricoli JV, Williams PM, Lubensky I, O'Sullivan-Coyne G, Kohn E, Little RF, White J, Malik S, Harris LN, Mann B, Weil C, Tarnuzzer R, Karlovich C, Rodgers B, Shankar L, Jacobs PM, Nolan T, Berryman SM, Gastier-Foster J, Bowen J, Leraas K, Shen H, Laird PW, Esteller M, Miller V, Johnson A, Edmondson EF, Giordano TJ, Kim B, Ivy SP.

J Natl Cancer Inst. 2020 Apr 27:djaa061.

doi: 10.1093/jnci/djaa061

MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

Mattesen TB, Rasmussen MH, Sandoval J, Ongen H, Árnadóttir SS, Gladov J, Martinez-Cardus A, Castro de Moura M, Madsen AH, Laurberg S, Dermitzakis ET, Esteller M, Andersen CL, Bramsen JB.

Nat Commun. 2020 Apr 24;11(1):2025.

doi: 10.1038/s41467-020-16000-6

A novel targeted RNA-Seq panel identifies a subset of adult patients with acute lymphoblastic leukemia with BCR-ABL1-like characteristics

Sánchez R, Ribera J, Morgades M, Ayala R, Onecha E, Ruiz-Heredia Y, Juárez-Rufián A, de Nicolás R, Sánchez-Pina J, Vives S, Zamora L, Mercadal S, Coll R, Cervera M, García O, Ribera JM, Martínez-López J.

Blood Cancer J. 2020 Apr 24;10(4):43.

doi: 10.1038/s41408-020-0308-3

Impaired Condensin Complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

Molina O, Vinyoles M, Granada I, Roca-Ho H, Gutierrez-Agüera F, Valledor L, López-López CM, Rodríguez-González P, Trincado JL, Tirados-Menéndez S, Pal D, Ballerini P, Den Boer ML, Plensa I, Perez-Iribarne MDM, Rodriguez-Perales S, Calasanz MJ, Ramírez M, Rodríguez R, Camos M, Calvo M, Bueno C, Menendez P.

Blood. 2020 Apr 22:blood.2019002538.

doi: 10.1182/blood.2019002538

A unique case of relapse of plasma cell leukemia in the vitreous humor

Franch-Sarto M, Anglada Escalona JR, Tuset Beltran V, Ribera Santasusana JM, Ferrà Coll C.

Leuk Res. 2020 Apr 21;93:106357.

doi: 10.1016/j.leukres.2020.106357

Biological and clinical significance of dysplastic hematopoiesis in patients with newly-diagnosed multiple myeloma.

Maia CADS, Puig N, Cedena MT, Goicoechea I, Valdés-Mas R, Vazquez I, Chillon MC, Aguirre P, Sarvide S, Gracia-Aznárez FJ, Alkorta-Aranburu G, Calasanz MJ, Garcia-Sanz R, González M, Gutierrez N, Martinez-Lopez J, Perez JJ, Merino J, Moreno C, Burgos L, Alignani D, Botta C, Prosper F, Matarraz S, Orfao A, Oriol A, Teruel AI, de Paz R, de Arriba F, Hernandez Garcia MT, Palomera L, Martinez R, Rosiñol L, Mateos MV, Lahuerta JJ, Bladé J, San Miguel J, Paiva B.

Blood. 2020 Apr 16:blood.2019003382.

doi: 10.1182/blood.2019003382

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

Pallarès V, Unzueta U, Falgàs A, Sánchez-García L, Serna N, Gallardo A, Morris GA, Alba-Castellón L, Álamo P, Sierra J, Villaverde A, Vázquez E, Casanova I, Mangues R.

J Hematol Oncol. 2020 Apr 15;13(1):36.

doi: 10.1186/s13045-020-00863-9

Long-term survival of 1338 MM patients treated with tandem autologous vs. autologous-allogeneic transplantation

Costa LJ, Iacobelli S, Pasquini MC, Modi R, Giaccone L, Blade J, Schonland S, Evangelista A, Perez-Simon JA, Hari P, Brown EE, Giralt SA, Patriarca F, Stadtmauer EA, Rosinol L, Krishnan AY, Gahrton G, Bruno B.

Bone Marrow Transplant. 2020 Apr 14.

doi: 10.1038/s41409-020-0887-4

Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma

Gonzalez-Santamarta M, Quinet G, Reyes-Garau D, Sola B, Roué G, Rodriguez MS.

Adv Exp Med Biol. 2020;1233:153-174.

doi: 10.1007/978-3-030-38266-7_6

Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study

Kim-Wanner SZ, Assenov Y, Nair MB, Weichenhan D, Benner A, Becker N, Landwehr K, Kuner R, Sültmann H, Esteller M, Koch I, Lindner M, Meister M, Thomas M, Bieg M, Klingmüller U, Schlesner M, Warth A, Brors B, Seifried E, Bönig H, Plass C, Risch A, Muley T.

J Thorac Oncol. 2020 Apr 7:S1556-0864(20)30287-2.

doi: 10.1016/j.jtho.2020.03.023